抗病毒疫苗

来源:公共卫生突发事件咨询服务与研究中心  作者:  发布时间:2003-07-03  查看次数:1459

    抗病毒疫苗是防治SARS最有效的途径。现在SARS病毒的序列已经确定,快速、有效、安全的制备抗SARS疫苗是当务之急。为此,CMBI搜集了目前国际上制备各种抗病毒疫苗的最新方法和文献,供大家参考。更多的文献资料,请访问CMBI的文献查询作进一步的了解。

 
非典型肺炎专题
 
ReviewDNA VaccineNeedle-Free VaccineAntibody engineering
Influenza VaccineAIDS VaccineHepatitis VaccineOther Viruses' Vaccine
Monoclonal AntibodyAntibacterial VaccineOthers 
 

Review

STRATEGIES FOR DESIGNING AND OPTIMIZING NEW GENERATION VACCINES

The global value of vaccination

The Intangible Value of Vaccination

Therapeutic antibodies

Therapeutic vaccination for spinal cord injury

Using Validation Sets for Outcomes and Exposure to Infection in Vaccine Field Studies

Transcutaneous immunization-A human vaccine delivery strategy using a patch

Recent developments in adjuvants for vaccines against infectious diseases

Can needle-free administration of vaccines become the norm in global immunization

Epidermal immunization by a needle-free powder delivery technology

Uses of granulocyte-macrophage colony-stimulating factor in vaccine development

THERAPEUTIC ANTIBODIES FOR HUMAN DISEASES AT THE DAWN OF THE TWENTY-FIRST CENTURY

Vaccinology-past achievements, present roadblocks and future promises

VACCINE SAFETY-VACCINE BENEFITS

Recent advances in mucosal vaccines and adjuvants

Vaccines aplenty

Vaccines-endangered species

vaccines-Ins and outs of clinical trials with peptide-based vaccines

Stimulation of local antibody production-parenteral or mucosal vaccination

vaccines and vaccination in the 21st century-

vaccines and vaccination in the 21st century-Aspects of cancer immunotherapy

vaccines and vaccination in the 21st century-Bacterial otitis media-Current vaccine development strategies

vaccines and vaccination in the 21st century-CPG ODN allows lower dose of antigen against hepatitis B surface antigen in BALBc mice

vaccines and vaccination in the 21st century-Generation of CTL responses using Kunjin replicon RNA

vaccines and vaccination in the 21st century-Hypoallergenic derivatives of major grass pollen allergens for allergy vaccination

vaccines and vaccination in the 21st century-Immune responses in hepatitis C virus infection

vaccines and vaccination in the 21st century-Immune responses to hepatitis B surface antigen following epidermal powder immunization

vaccines and vaccination in the 21st century-Improving vaccines against tuberculosis

vaccines and vaccination in the 21st century-Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus

vaccines and vaccination in the 21st century-Mucosal immunity

Quantitative approaches to computational vaccinology

Promising vaccines for infectious diseases

Antibody Design by Man and Nature

Antibody evolution beyond Nature

Clinically useful monoclonal antibodies in treatment

Direct detection of antibody-antigen binding using an on-chip artificial pore

EFFECTOR AND MEMORY T-CELL DIFFERENTIATION-IMPLICATIONS FOR VACCINE DEVELOPMENT

New vaccine development

ETHICAL ISSUES FOR VACCINES AND IMMUNIZATION

Future prospects for vaccines to control fertility

Bacterial infectious disease control by vaccine development

Lactobacilli as live vaccine delivery vectors

Nasal vaccination induces protective immunity without immunopathology

New directions in vaccine research

Processing and presentation of antigens by dendritic cells-implications for vaccines

RNA viruses-emerging vectors for vaccination and gene therapy

Recent advances with recombinant bacterial vaccine vectors

Immunological adjuvants in allergy vaccines: Past, present and future

Antibacterial vaccine design using genomics and proteomics

Immunomodulators and delivery systems for vaccination by mucosal routes

Exploiting dendritic cells to improve vaccine efficacy

From genome to vaccine

Approaches to MHC-based vaccination

Prospects for Vaccines to Protect Against AIDS, Tuberculosis, and Malaria

Construction of a novel set of transfer vectors to study vaccinia virus replication and foreign gene expression

ANTIBODIES, VIRUSES AND VACCINES

Quantitative approaches to computational vaccinology

Mining genomes for vaccine components

STRATEGIES FOR DESIGNING AND OPTIMIZING NEW GENERATION VACCINES

Arrested Differentiation, the Self-Renewing Memory Lymphocyte, and Vaccination

Alphavirus vectors and vaccination

Infections Associated with Health-care Personnel-Vaccine-preventable Diseases and Bloodborne Pathogens

Next generation therapeutics-Random-peptide libraries and antigen-fragment libraries and the development of vaccines and diagnostics

New organisms, new syndromes and new vaccines

The adverse effects of vaccines-fact and fiction

Immunocontraceptive vaccines for human use

The role of mass spectrometry in vaccine development

Oral vaccination in man using antigens in particles-current status

Vaccine research and development

Top

DNA Vaccine

DNA50-Gene Vaccines

DNA vaccines

Gene Vaccines

DNA-based vaccination for the treatment of food allergy

Dendritic cell discoveries provide new insight into the cellular immunobiology of DNA vaccines

A cationic sub-micron emulsion (MF59/DOTAP) is an effective delivery system for DNA vaccines

The Development of Polyplex-based DNA Vaccines

DNA vaccination: antigen presentation and the induction of immunity

Antigen-Specific Mediated Suppression of Cell Autoimmunity by Plasmid DNA Vaccination

DNA Vaccines — Designer Vaccines for the 21st Century

The Molecular Surgeon-DNA and RNA Modified Dendritic Cell Vaccines

vaccination-Mucosa-targeted DNA vaccination

vaccination-Oral DNA vaccination-antigen uptake and presentation by dendritic cells elicits protective immunity

Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways

DNA and RNA Modified Dendritic Cell Vaccines

Oral DNA vaccination with a plasmid encoding soluble ICAM-1 modulates cytokine expression profiles in nonobese diabetic mice

Progress in DNA vaccine for prophylaxis and therapy of hepatitis B

vaccines-Anti-idiotypic DNA vaccines for B-cell lymphoma therapy

The Potential of DNA Vaccination against Tumor-Associated Antigens for Antitumor Therapy

Virus-like particle and DNA-based candidate AIDS vaccines

Fetal immunization by a DNA vaccine delivered into the oral cavity

Oral DNA vaccination: antigen uptake and presentation by dendritic cells elicits protective immunity

Mucosa-targeted DNA vaccination

DNA shuffling: induced molecular breeding to produce new generation long-lasting vaccines

Top

Needle-Free Vaccination

Fetal immunization by a DNA vaccine delivered into the oral cavity

Can needle-free administration of vaccines become the norm in global immunization

Epidermal immunization by a needle-free powder delivery technology

Improved genetic immunization via micromechanical disruption of skin-barrier targeted epidermal delivery

Production of hepatitis B surface antigen in transgenic plants for oral immunization

Transcutaneous immunization- A human vaccine delivery strategy using a patch

Top

Antibody engineering

Antibody engineering and its applications in tumor targeting and intracellular immunization

Antibody gene therapy

Chemical engineering of cell penetrating antibodies

Engineered antibodies

Engineering receptors and antibodies for biosensors

High-throughput generation and engineering of recombinant human antibodies

Human antibody kills tumors by direct signaling

Improving the efficacy of antibody-based cancer therapies

Individually addressable parallel peptide synthesis on microchips

Ligand-targeted therapeutics in anticancer therapy

monoclonal antibodies efficiently induce programmed death of malignant lymphoid cells

Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity

The roots of antibody diversity

Therapeutic antibodies

Top

Influenza Vaccine

Evidence-Based-inactivated vaccines provide the greatest protection against influenza in healthy people

public healthConsiderations for adding pneumonia and influenza vaccines to public health programmes

The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus,Implications for peptide vaccination

Influenza virosomes

Novel approaches in the development of immunopotentiating reconstituted influenza virosomes

vaccines-Current overview of the pathogenesis and prophylaxis of measles with focus on practical implications

vaccines-Influenza vaccines-present and future

The rationale of a peptide-conjugate vaccine against measles

Association Between Influenza Vaccination and Reduced Risk of Brain Infarction

A novel bioadhesive intranasal delivery system for inactivated influenza vaccines

Vaccination against infections by Chlamydia pneumoniae

Top

AIDS Vaccine

Challenges in the Development of an Effective HIV Vaccine

Control of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA-MVA Vaccine

Control of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA-MVA Vaccine

Crystal Structure of a Neutralizing Human IgG Against HIV-1- A Template for Vaccine Design

Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity

PROSPECTS FOR VACCINE PROTECTION AGAINST HIV-1 INFECTION AND AIDS

AIDS vaccine models-Challenging challenge viruses

AIDS vaccines-On the trail of two trials

HIV Vaccine Development in the Nonhuman Primate

HIV-changing face-Prospect of a prophylactic vaccine for HIV

hiv-Diversity Considerations in HIV-1 Vaccine Selection

hiv-Genetic Subtypes, Humoral Immunity, and Human Immunodeficiency Virus Type 1 Vaccine Development

hiv-High hopes for HIV vaccine

hiv-Prospect of a prophylactic vaccine for HIV

hiv-Will we be able to ‘spot’ an effective HIV-1 vaccine

CLINICAL TRIALS OF HIV VACCINES

Public health paradoxes and the epidemiological impact of an HPV vaccine

Rational development of prophylactic HIV vaccines based on structural and regulatory proteins

A new generation of HIV vaccine.

A review of vaccines for HIV prevention

AIDS vaccines models-challenging challenge viruses

Challenges and opportunities for development of an AIDS vaccine

HIV-1 Vaccine Race

Introduction of a HIV vaccine in developing countries

NEW HOPE FOR AN AIDS VACCINE

Prospects and challenges for prophylactic and therapeutic HIV vaccines

PROSPECTS FOR VACCINE PROTECTIOn against HIV-1 INFECTION AND AIDS.

Vaccines for HIV in the developing world

vaccines-basis for HIV immunotherapeutic vaccines

Strategies for an HIV vaccine

Therapeutic dendritic-cell vaccine for simian AIDS

Therapeutic vaccination for future management of HIV-AIDS

V-1 Immunitor-oral therapeutic AIDS vaccine with prophylactic potential

Top

Hepatitis Vaccine

Magnitude and quality of antibody response to a combination hepatitis A and hepatitis B vaccine

Hepatitis A, Hepatitis B, and Combination Hepatitis Vaccines for Immunoprophylaxis

Hepatitis B vaccine-do we need boosters

hepatitis-Combined hepatitis B vaccines

hepatitis-Perspectives for a hepatitis C virus vaccine

Hepatitis-vaccine-

hepatitis-vaccine-Hepatitis B vaccine

Recombinant vaccines for hepatitis E

Hepatitis B vaccines

Hepatitis A vaccine development-a personal perspective

Primary prevention of hepatitis C virus infection

vaccines-Peptide vaccines against hepatitis B virus

vaccines-towards a peptide-based vaccine against hepatitis C virus

Vaccination with an adenoviral vector encoding hepatitis C virus (HCV) NS3 protein protects against infection with HCV-recombinant vaccinia virus

Production of hepatitis B surface antigen in transgenic plants for oral immunization

Vaccine-and Hepatitis B Immune Globulin-Induced Escape Mutations of Hepatitis B Virus Surface Antigen

Top

Other Viruses' Vaccine

Molecular Analyses of Oral Polio Vaccine Samples

Protective autoimmunity-regulation and prospects for vaccination after brain and spinal cord injuries

Eradication of Poliomyelitis

Ebola Vaccine Progress

Ebola virus-the search for vaccines and treatments

anthrax-Smallpox vaccine development quickened

Evaluation of 21st-Century Risks of Smallpox Vaccination and Policy Options

Influenza vaccination for healthy children

Influenza vaccination in old age

Smallpox vaccination techniques

Studies in smallpox and vaccination

Smallpox and the smallpox vaccine controversy

Recent advances in vaccines against viral haemorrhagic fevers

Yellow fever vector live-virus vaccines

Measles vaccine could treat lymphoma

Top

Monoclonal Antibody

Monoclonal antibodies inhibit prion replication and delay the development of prion disease

Monoclonal antibodies-Antibody discovery-phage display

Monoclonal antibodies-Antibody discovery-the use of transgenic mice to generate human monoclonal antibodies for therapeutics

Monoclonal antibodies-Antibody manufacture in transgenic animals and comparisons with other systems

Monoclonal antibodies-Anti-R7V antibodies as therapeutics for HIV-infected patients in failure of HAART

Monoclonal antibodies-boundless potential, daunting challenges

Monoclonal antibodies-Monoclonal antibodies as therapeutics in oncology

Monoclonal antibodies-Monoclonal antibodies in immune and inflammatory diseases

Monoclonal antibodies-Monoclonal antibody manufacturing in transgenic plants ?a myths and realities

Monoclonal antibodies-Pharmacokinetics and biodistribution of genetically engineered antibodies

Monoclonal Antibody Therapy of Haematological Malignancies

Monoclonal Antibody-Based Therapy Strategies-Providing Options for the Cancer Patient

Top

Antibacterial Vaccine

TB vaccines- progress and problems

tb-The search for new vaccines against tuberculosis

tb-Vaccination against and treatment of tuberculosis

Tuberculosis vaccine development

Is the development of a new tuberculosis vaccine possible

A novel TB vaccine

tb-HOW CAN IMMUNOLOGY CONTRIBUTE TO THE CONTROL OF TUBERCULOSIS

New therapies and vaccines for bacterial meningitis

Vaccine prevention of meningococcal disease

Progress towards developing a vaccine for group A streptococcus based on the M protein

Use of Pneumococcal Polysaccharide Vaccines

Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays

Progress in vaccination against Helicobacter pylori

THE DESIGN OF VACCINES AGAINST HELICOBACTER PYLORI AND THEIR DEVELOPMENT

Helicobacter pylori vaccines-the current status

Helicobacter pylori vaccine strategies_triggering a gut reaction

Salmonella vaccines for use in humans-present and future perspectives

pneumococcus-carriage, disease and conjugate vaccines

Pneumococcal conjugate vaccine

Respiratory syncytial virus vaccine development

PNEUMOCOCCAL AND INFLUENZA VACCINATION

TOWARDS A BLOOD-STAGE VACCINE FOR MALARIA-ARE WE FOLLOWING ALL THE LEADS

Malaria-from Infants to Genomics to Vaccines

Malaria-Sequencing of the Malaria Genome Opens Door to Vaccines and New Drugs

malaria-Progress and challenges for malaria vaccines

Evidence-Based-Novel Plasmodium falciparum malaria vaccines

DNA-based vaccines against malaria

Immunity to asexual blood stage malaria and vaccine approaches

Malaria-specific antibody subclasses in immune individuals

Progress and challenges for malaria vaccines

Prospects for a vaccine against malaria

Sequencing of the malaria genome opens door to vaccines and new drugs

vaccines-malaria vaccine development

vaccines-Peptide-based subunit vaccines against pre-erythrocytic stages of malaria parasites

Top

Others

Vaccination to prevent varicella and shingles

How Contagious Is Vaccinia

vaccination-Generation of therapeutic antibody responses against IgE through vaccination

A novel human immunoglobulin Fc-Fc bifunctional fusion protein inhibits FcRI-mediated degranulation

Novel vaccines protecting against the development of allergic disorders

vaccines-chain lipopeptide vaccines for the induction of virus-specific cytotoxic T cell responses in randomly selected populations

vaccines-T-cell vaccination for autoimmune disease

Bacterial vaccines: anything but placebo

Could administration of bacille Calmette-Guerin vaccination at birth protect from the development of asthma and allergic diseases in the western world? Has this question been adequately investigated?

A future vaccine for diabetes

Vaccination against infections by Chlamydia pneumoniae

A vaccine against atherosclerosis

Could vaccinations prevent myocardial infarction

Salmonella vaccines for use in humans-present and future perspectives

Generation of antibodies specific for-amyloid by vaccination of patients with Alzheimer disease

New hope for Alzheimer disease vaccine

CNS injury- prospects for vaccination

Inflammation and therapeutic vaccination in CNS diseases

Towards a vaccine for Alzheimer disease

vaccination-Neurological adverse events associated with vaccination

An Assessment of Thimerosal Use in Childhood Vaccines

Do Multiple Vaccines Overwhelm or Weaken the Infant’s Immune System

vaccination at birth protect from the development of allergic diseases

The current status of vaccine-preventable infections

Child vaccination policies in Europe

Recent progress in the development of vaccines for infants and children

Vaccines for children

The development of contraceptive vaccines

Antifertility vaccines