来源:公共卫生突发事件咨询服务与研究中心 作者: 发布时间:2003-07-03 查看次数:1459
抗病毒疫苗是防治SARS最有效的途径。现在SARS病毒的序列已经确定,快速、有效、安全的制备抗SARS疫苗是当务之急。为此,CMBI搜集了目前国际上制备各种抗病毒疫苗的最新方法和文献,供大家参考。更多的文献资料,请访问CMBI的文献查询作进一步的了解。
Review
STRATEGIES FOR DESIGNING AND OPTIMIZING NEW GENERATION VACCINESThe global value of vaccinationThe Intangible Value of VaccinationTherapeutic antibodiesTherapeutic vaccination for spinal cord injuryUsing Validation Sets for Outcomes and Exposure to Infection in Vaccine Field StudiesTranscutaneous immunization-A human vaccine delivery strategy using a patchRecent developments in adjuvants for vaccines against infectious diseasesCan needle-free administration of vaccines become the norm in global immunizationEpidermal immunization by a needle-free powder delivery technologyUses of granulocyte-macrophage colony-stimulating factor in vaccine developmentTHERAPEUTIC ANTIBODIES FOR HUMAN DISEASES AT THE DAWN OF THE TWENTY-FIRST CENTURYVaccinology-past achievements, present roadblocks and future promisesVACCINE SAFETY-VACCINE BENEFITSRecent advances in mucosal vaccines and adjuvantsVaccines aplentyVaccines-endangered speciesvaccines-Ins and outs of clinical trials with peptide-based vaccinesStimulation of local antibody production-parenteral or mucosal vaccinationvaccines and vaccination in the 21st century-vaccines and vaccination in the 21st century-Aspects of cancer immunotherapyvaccines and vaccination in the 21st century-Bacterial otitis media-Current vaccine development strategiesvaccines and vaccination in the 21st century-CPG ODN allows lower dose of antigen against hepatitis B surface antigen in BALBc micevaccines and vaccination in the 21st century-Generation of CTL responses using Kunjin replicon RNAvaccines and vaccination in the 21st century-Hypoallergenic derivatives of major grass pollen allergens for allergy vaccinationvaccines and vaccination in the 21st century-Immune responses in hepatitis C virus infectionvaccines and vaccination in the 21st century-Immune responses to hepatitis B surface antigen following epidermal powder immunizationvaccines and vaccination in the 21st century-Improving vaccines against tuberculosisvaccines and vaccination in the 21st century-Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virusvaccines and vaccination in the 21st century-Mucosal immunityQuantitative approaches to computational vaccinologyPromising vaccines for infectious diseasesAntibody Design by Man and NatureAntibody evolution beyond NatureClinically useful monoclonal antibodies in treatmentDirect detection of antibody-antigen binding using an on-chip artificial poreEFFECTOR AND MEMORY T-CELL DIFFERENTIATION-IMPLICATIONS FOR VACCINE DEVELOPMENTNew vaccine developmentETHICAL ISSUES FOR VACCINES AND IMMUNIZATIONFuture prospects for vaccines to control fertilityBacterial infectious disease control by vaccine developmentLactobacilli as live vaccine delivery vectorsNasal vaccination induces protective immunity without immunopathologyNew directions in vaccine researchProcessing and presentation of antigens by dendritic cells-implications for vaccinesRNA viruses-emerging vectors for vaccination and gene therapyRecent advances with recombinant bacterial vaccine vectorsImmunological adjuvants in allergy vaccines: Past, present and futureAntibacterial vaccine design using genomics and proteomicsImmunomodulators and delivery systems for vaccination by mucosal routesExploiting dendritic cells to improve vaccine efficacyFrom genome to vaccineApproaches to MHC-based vaccinationProspects for Vaccines to Protect Against AIDS, Tuberculosis, and MalariaConstruction of a novel set of transfer vectors to study vaccinia virus replication and foreign gene expressionANTIBODIES, VIRUSES AND VACCINESQuantitative approaches to computational vaccinologyMining genomes for vaccine componentsSTRATEGIES FOR DESIGNING AND OPTIMIZING NEW GENERATION VACCINESArrested Differentiation, the Self-Renewing Memory Lymphocyte, and VaccinationAlphavirus vectors and vaccinationInfections Associated with Health-care Personnel-Vaccine-preventable Diseases and Bloodborne PathogensNext generation therapeutics-Random-peptide libraries and antigen-fragment libraries and the development of vaccines and diagnosticsNew organisms, new syndromes and new vaccinesThe adverse effects of vaccines-fact and fictionImmunocontraceptive vaccines for human useThe role of mass spectrometry in vaccine developmentOral vaccination in man using antigens in particles-current statusVaccine research and development
Top
DNA Vaccine
DNA50-Gene VaccinesDNA vaccinesGene VaccinesDNA-based vaccination for the treatment of food allergyDendritic cell discoveries provide new insight into the cellular immunobiology of DNA vaccinesA cationic sub-micron emulsion (MF59/DOTAP) is an effective delivery system for DNA vaccinesThe Development of Polyplex-based DNA VaccinesDNA vaccination: antigen presentation and the induction of immunityAntigen-Specific Mediated Suppression of Cell Autoimmunity by Plasmid DNA VaccinationDNA Vaccines — Designer Vaccines for the 21st CenturyThe Molecular Surgeon-DNA and RNA Modified Dendritic Cell Vaccinesvaccination-Mucosa-targeted DNA vaccinationvaccination-Oral DNA vaccination-antigen uptake and presentation by dendritic cells elicits protective immunityAlphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathwaysDNA and RNA Modified Dendritic Cell VaccinesOral DNA vaccination with a plasmid encoding soluble ICAM-1 modulates cytokine expression profiles in nonobese diabetic miceProgress in DNA vaccine for prophylaxis and therapy of hepatitis Bvaccines-Anti-idiotypic DNA vaccines for B-cell lymphoma therapyThe Potential of DNA Vaccination against Tumor-Associated Antigens for Antitumor TherapyVirus-like particle and DNA-based candidate AIDS vaccinesFetal immunization by a DNA vaccine delivered into the oral cavityOral DNA vaccination: antigen uptake and presentation by dendritic cells elicits protective immunityMucosa-targeted DNA vaccinationDNA shuffling: induced molecular breeding to produce new generation long-lasting vaccines
Needle-Free Vaccination
Fetal immunization by a DNA vaccine delivered into the oral cavityCan needle-free administration of vaccines become the norm in global immunizationEpidermal immunization by a needle-free powder delivery technologyImproved genetic immunization via micromechanical disruption of skin-barrier targeted epidermal deliveryProduction of hepatitis B surface antigen in transgenic plants for oral immunizationTranscutaneous immunization- A human vaccine delivery strategy using a patch
Antibody engineering
Antibody engineering and its applications in tumor targeting and intracellular immunizationAntibody gene therapyChemical engineering of cell penetrating antibodiesEngineered antibodiesEngineering receptors and antibodies for biosensorsHigh-throughput generation and engineering of recombinant human antibodiesHuman antibody kills tumors by direct signalingImproving the efficacy of antibody-based cancer therapiesIndividually addressable parallel peptide synthesis on microchipsLigand-targeted therapeutics in anticancer therapymonoclonal antibodies efficiently induce programmed death of malignant lymphoid cellsProtection against anthrax toxin by recombinant antibody fragments correlates with antigen affinityThe roots of antibody diversityTherapeutic antibodies
Influenza Vaccine
Evidence-Based-inactivated vaccines provide the greatest protection against influenza in healthy peoplepublic healthConsiderations for adding pneumonia and influenza vaccines to public health programmesThe principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus,Implications for peptide vaccinationInfluenza virosomesNovel approaches in the development of immunopotentiating reconstituted influenza virosomesvaccines-Current overview of the pathogenesis and prophylaxis of measles with focus on practical implicationsvaccines-Influenza vaccines-present and futureThe rationale of a peptide-conjugate vaccine against measlesAssociation Between Influenza Vaccination and Reduced Risk of Brain InfarctionA novel bioadhesive intranasal delivery system for inactivated influenza vaccinesVaccination against infections by Chlamydia pneumoniae
AIDS Vaccine
Challenges in the Development of an Effective HIV VaccineControl of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA-MVA VaccineControl of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA-MVA VaccineCrystal Structure of a Neutralizing Human IgG Against HIV-1- A Template for Vaccine DesignCoadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunityPROSPECTS FOR VACCINE PROTECTION AGAINST HIV-1 INFECTION AND AIDSAIDS vaccine models-Challenging challenge virusesAIDS vaccines-On the trail of two trialsHIV Vaccine Development in the Nonhuman PrimateHIV-changing face-Prospect of a prophylactic vaccine for HIVhiv-Diversity Considerations in HIV-1 Vaccine Selectionhiv-Genetic Subtypes, Humoral Immunity, and Human Immunodeficiency Virus Type 1 Vaccine Developmenthiv-High hopes for HIV vaccinehiv-Prospect of a prophylactic vaccine for HIVhiv-Will we be able to ‘spot’ an effective HIV-1 vaccineCLINICAL TRIALS OF HIV VACCINESPublic health paradoxes and the epidemiological impact of an HPV vaccineRational development of prophylactic HIV vaccines based on structural and regulatory proteinsA new generation of HIV vaccine.A review of vaccines for HIV preventionAIDS vaccines models-challenging challenge virusesChallenges and opportunities for development of an AIDS vaccineHIV-1 Vaccine RaceIntroduction of a HIV vaccine in developing countriesNEW HOPE FOR AN AIDS VACCINEProspects and challenges for prophylactic and therapeutic HIV vaccinesPROSPECTS FOR VACCINE PROTECTIOn against HIV-1 INFECTION AND AIDS.Vaccines for HIV in the developing worldvaccines-basis for HIV immunotherapeutic vaccinesStrategies for an HIV vaccineTherapeutic dendritic-cell vaccine for simian AIDSTherapeutic vaccination for future management of HIV-AIDSV-1 Immunitor-oral therapeutic AIDS vaccine with prophylactic potential
Hepatitis Vaccine
Magnitude and quality of antibody response to a combination hepatitis A and hepatitis B vaccineHepatitis A, Hepatitis B, and Combination Hepatitis Vaccines for ImmunoprophylaxisHepatitis B vaccine-do we need boostershepatitis-Combined hepatitis B vaccineshepatitis-Perspectives for a hepatitis C virus vaccineHepatitis-vaccine-hepatitis-vaccine-Hepatitis B vaccineRecombinant vaccines for hepatitis EHepatitis B vaccinesHepatitis A vaccine development-a personal perspectivePrimary prevention of hepatitis C virus infectionvaccines-Peptide vaccines against hepatitis B virusvaccines-towards a peptide-based vaccine against hepatitis C virusVaccination with an adenoviral vector encoding hepatitis C virus (HCV) NS3 protein protects against infection with HCV-recombinant vaccinia virusProduction of hepatitis B surface antigen in transgenic plants for oral immunizationVaccine-and Hepatitis B Immune Globulin-Induced Escape Mutations of Hepatitis B Virus Surface Antigen
Other Viruses' Vaccine
Molecular Analyses of Oral Polio Vaccine SamplesProtective autoimmunity-regulation and prospects for vaccination after brain and spinal cord injuriesEradication of Poliomyelitis
Ebola Vaccine ProgressEbola virus-the search for vaccines and treatments
anthrax-Smallpox vaccine development quickenedEvaluation of 21st-Century Risks of Smallpox Vaccination and Policy OptionsInfluenza vaccination for healthy childrenInfluenza vaccination in old ageSmallpox vaccination techniquesStudies in smallpox and vaccinationSmallpox and the smallpox vaccine controversy
Recent advances in vaccines against viral haemorrhagic feversYellow fever vector live-virus vaccines
Measles vaccine could treat lymphoma
Monoclonal Antibody
Monoclonal antibodies inhibit prion replication and delay the development of prion diseaseMonoclonal antibodies-Antibody discovery-phage displayMonoclonal antibodies-Antibody discovery-the use of transgenic mice to generate human monoclonal antibodies for therapeuticsMonoclonal antibodies-Antibody manufacture in transgenic animals and comparisons with other systemsMonoclonal antibodies-Anti-R7V antibodies as therapeutics for HIV-infected patients in failure of HAARTMonoclonal antibodies-boundless potential, daunting challengesMonoclonal antibodies-Monoclonal antibodies as therapeutics in oncologyMonoclonal antibodies-Monoclonal antibodies in immune and inflammatory diseasesMonoclonal antibodies-Monoclonal antibody manufacturing in transgenic plants ?a myths and realitiesMonoclonal antibodies-Pharmacokinetics and biodistribution of genetically engineered antibodiesMonoclonal Antibody Therapy of Haematological MalignanciesMonoclonal Antibody-Based Therapy Strategies-Providing Options for the Cancer Patient
Antibacterial Vaccine
TB vaccines- progress and problemstb-The search for new vaccines against tuberculosistb-Vaccination against and treatment of tuberculosisTuberculosis vaccine developmentIs the development of a new tuberculosis vaccine possibleA novel TB vaccinetb-HOW CAN IMMUNOLOGY CONTRIBUTE TO THE CONTROL OF TUBERCULOSIS
New therapies and vaccines for bacterial meningitisVaccine prevention of meningococcal diseaseProgress towards developing a vaccine for group A streptococcus based on the M proteinUse of Pneumococcal Polysaccharide VaccinesPreviously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays
Progress in vaccination against Helicobacter pyloriTHE DESIGN OF VACCINES AGAINST HELICOBACTER PYLORI AND THEIR DEVELOPMENTHelicobacter pylori vaccines-the current statusHelicobacter pylori vaccine strategies_triggering a gut reaction
Salmonella vaccines for use in humans-present and future perspectives
pneumococcus-carriage, disease and conjugate vaccinesPneumococcal conjugate vaccineRespiratory syncytial virus vaccine developmentPNEUMOCOCCAL AND INFLUENZA VACCINATION
TOWARDS A BLOOD-STAGE VACCINE FOR MALARIA-ARE WE FOLLOWING ALL THE LEADSMalaria-from Infants to Genomics to VaccinesMalaria-Sequencing of the Malaria Genome Opens Door to Vaccines and New Drugsmalaria-Progress and challenges for malaria vaccinesEvidence-Based-Novel Plasmodium falciparum malaria vaccinesDNA-based vaccines against malariaImmunity to asexual blood stage malaria and vaccine approachesMalaria-specific antibody subclasses in immune individualsProgress and challenges for malaria vaccinesProspects for a vaccine against malariaSequencing of the malaria genome opens door to vaccines and new drugsvaccines-malaria vaccine developmentvaccines-Peptide-based subunit vaccines against pre-erythrocytic stages of malaria parasites
Others
Vaccination to prevent varicella and shinglesHow Contagious Is Vacciniavaccination-Generation of therapeutic antibody responses against IgE through vaccinationA novel human immunoglobulin Fc-Fc bifunctional fusion protein inhibits FcRI-mediated degranulationNovel vaccines protecting against the development of allergic disordersvaccines-chain lipopeptide vaccines for the induction of virus-specific cytotoxic T cell responses in randomly selected populationsvaccines-T-cell vaccination for autoimmune diseaseBacterial vaccines: anything but placeboCould administration of bacille Calmette-Guerin vaccination at birth protect from the development of asthma and allergic diseases in the western world? Has this question been adequately investigated?A future vaccine for diabetesVaccination against infections by Chlamydia pneumoniaeA vaccine against atherosclerosisCould vaccinations prevent myocardial infarctionSalmonella vaccines for use in humans-present and future perspectivesGeneration of antibodies specific for-amyloid by vaccination of patients with Alzheimer diseaseNew hope for Alzheimer disease vaccineCNS injury- prospects for vaccinationInflammation and therapeutic vaccination in CNS diseasesTowards a vaccine for Alzheimer diseasevaccination-Neurological adverse events associated with vaccinationAn Assessment of Thimerosal Use in Childhood VaccinesDo Multiple Vaccines Overwhelm or Weaken the Infant’s Immune Systemvaccination at birth protect from the development of allergic diseasesThe current status of vaccine-preventable infectionsChild vaccination policies in EuropeRecent progress in the development of vaccines for infants and childrenVaccines for childrenThe development of contraceptive vaccinesAntifertility vaccines